Wolff is the surname of:
- Albert Wolff (conductor), Dutch conductor and pianist
- Albert Wolff (sculptor) (1814–1892), German sculptor
- Albert Moritz Wolff (1854–1923), German sculptor
- Albert Wolff (Australian judge)
- Alexander Wolff, American writer
- Alex Wolff, American actor
- Aronte Wolff Berlijn (1817-1870) holander composer.
- Lt Col Alexander Wolff, (1788–1863), British officer who served under the Duke of Wellington
- Betje Wolff (1738–1804), Dutch writer
- Bernard Wolff (1811–1879), German media mogul
- Bernard Pierre Wolff (1930–1985), French photographer
- Beverly Wolff (1928–2005), American mezzo-soprano
- Bobby Wolff (born 1932), American bridge player
- Carl Gustaf Wolff, a prominent Finnish shipowner and businessman
- Caspar Friedrich Wolff (1734–1794), founder of embryology
- Christian Wolff (philosopher) (1679–1754), German philosopher and mathematician
- Christian Wolff (composer) (born 1934), American composer of experimental classical music
- Christian Wolff (actor), German actor
- Christoph Wolff (born 1940), German-born musicologist
- David Wolff, music producer
- Edward Wolff (born 1946), American economist
- Magda Lupescu (1895?–1977), mistress and (after his abdication) wife of Carol II of Romania Lupescu is a Romanianization of Wolff
- Enrique Wolff (born 1949), Argentine football player
- Ernst Victor Wolff (1886–1961), German-born classical pianist and harpsichordist
- Francis Wolff, photographer and the founder of Blue Note Records
- Frank Wolff (disambiguation), several people
- Franklin Merrell-Wolff (1887–1985), an American mystical philosopher
- Freddie Wolff (1910–1988), British sprinter
- Geoffrey Wolff (born 1937), American writer
- Gerald W. Wolff (born 1939), American historian
- Hans Walter Wolff (born 1911), German biblical scholar
- Hellmuth Wolff (born 1937), Canadian organ builder
- Heinz Wolff (born 1928), German-British scientist and television and radio presenter
- Henry Drummond Wolff (1830–1908), English diplomat
- Hugo Wolff (1860–1903), Austrian composer
- Jonathan Wolff (born 1959), philosopher and Marxist scholar
- Jonathan Wolff, composer of the Seinfeld TV theme
- Josh Wolff (born 1977), American soccer player
- Joseph Wolff (1795–1862), Jewish Christian missionary from Germany
- Julius Wolff (1836–1902), surgeon
- Julius Wolff (mathematician) (1882-1945), Dutch mathematician
- Kurt Wolff (WWI Ace) (1895–1917), German World War I pilot and Ace
- Louis Wolff (1898–1972), American cardiologist
- Karin Wolff (1959), German politician
- Karl Wolff (1900–1984), high-ranking member of the Schutzstaffel
- Leon Wolff historian, author
- Maritta Wolff (1918–2002) American novelist
- Milton Wolff Commander of the Lincoln Battalion
- Nelson Wolff (born 1940), American politician
- Patrick Wolff (born 1968), American chess player
- Richard D. Wolff (born 1942), American economist
- Richard Keith Wolff (born 1947), British photographer
- Rikard Wolff (born 1958), Swedish actor
- Robert Paul Wolff, political philosopher
- Roger Wolff (1911–1994), American baseball player
- Scott Wolff Founder of WOLFF & Associates Consulting for DITA
- Stefan Wolff, German political scientist and professor living in the UK
- Sula Wolff
- Tobias Wolff (born 1945), American writer
- Toto Wolff (born 1972), Austrian racing driver and investor
- Thomas Wolff (1954–2000), American mathematician
- Werner Wolff (musician)
- Werner Wolff, SS officer
Wolff can also refer to:
- Harland and Wolff, shipbuilding company
- Wolff & Associés, organ building company
- Rudolf Wolff & Co, commodity broker
- Nelson W. Wolff Municipal Stadium
- Wolff-Kishner reduction
- Wolff-Parkinson-White syndrome