William Gore may refer to:
- William Gore (15th-century MP) for Maldon (UK Parliament constituency)
- Sir William Gore, 3rd Baronet (died 1700), Irish Custos Rotulorum of Leitrim
- William Gore (died 1739) (c. 1675–1739), English MP for Colchester, Cricklade and St Albans
- William Gore (Lord Mayor of London) (died 1708), Lord Mayor of London 1701
- William Crampton Gore (1871–1946), Irish artist
- William Ormsby-Gore, 2nd Baron Harlech (1819–1904), MP for Sligo in the British Parliament (1841–1852)
- William Ormsby-Gore, 4th Baron Harlech (1885–1964), British MP and Cabinet Minister
- William Ormsby-Gore, 5th Baron Harlech (1918–1985), British MP for Oswestry (1950–1964)
- Bill Gore (1912–1986), American chemical engineer
- William Gore Ouseley (1797–1866), British diplomat
- William Gore (bishop) 18th century Irish Anglican Bishop
- Parliament of Ireland
- William Gore (died 1730), MP for Leitrim 1703–1730, Donegal Borough
- William Gore (1703–1748), MP for Kilkenny City
- William Gore (1709–1769), MP for Leitrim 1730–1760 and 1768–1769
- William Gore (1744–1815), MP for Leitrim 1769–1776
- William Gore (1767–1832), MP for Carrick