Others
- William Cook (entrepreneur) (1931–2011), founder of the Cook Group, medical equipment manufacturer
- William Edwards Cook (1881–1959), American-born expatriate artist, architectural patron, and long-time friend of writer Gertrude Stein
- William Cook, 19th/early 20th century creator of the Orpington poultry breeds
- William Douglas Cook (1884–1967), founder of Eastwoodhill Arboretum, now the national arboretum of New Zealand
- William Harrison Cook (1903–1998), Canadian chemist
- William R. Cook, American history professor, collaborator with Ron Herzman
- William Cook (computer scientist) (born 1963), American computer scientist
- Billy Cook (actor) (1928–1981), American actor
- Billy Cook (criminal) (1928–1952), American mass murderer
- Will Cook (writer) (William Everett Cook, 1921–1964), American writer of westerns
- William Delafield Cook, Australian artist
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