Substance may refer to:
- Chemical substance, a material with a definite chemical composition
- Drug substance
- Substance abuse, drug-related healthcare and social policy diagnosis or label
- Substance dependence, drug-related healthcare and social policy diagnosis or label
- Matter, anything that has mass and takes up space
- Substance theory, theory positing that a substance is distinct from its properties
- Substantial (rapper) a US musician
- Substance (Joy Division album), 1988
- Substance (Blank & Jones album), 2002
- Substance 1987, a New Order album
- "Substance", a song by Haste the Day from That They May Know You
- Metal Gear Solid 2: Substance, an update of the video game Metal Gear Solid 2: Sons of Liberty
- Homoousian, a Christian term meaning "same substance"
Famous quotes containing the word substance:
“Leave everything. Leave Dada. Leave your wife. Leave your mistress. Leave your hopes and fears. Leave your children in the woods. Leave the substance for the shadow. Leave your easy life, leave what you are given for the future. Set off on the roads.”
—André Breton (1896–1966)
“We are nothing but ceremony; ceremony carries us away, and we leave the substance of things; we hang on to the branches and abandon the trunk and body.”
—Michel de Montaigne (1533–1592)
“What is a country without rabbits and partridges? They are among the most simple and indigenous animal products; ancient and venerable families known to antiquity as to modern times; of the very hue and substance of Nature, nearest allied to leaves and to the ground,—and to one another; it is either winged or it is legged. It is hardly as if you had seen a wild creature when a rabbit or a partridge bursts away, only a natural one, as much to be expected as rustling leaves.”
—Henry David Thoreau (1817–1862)