Substance may refer to:
- Chemical substance, a material with a definite chemical composition
- Drug substance
- Substance abuse, drug-related healthcare and social policy diagnosis or label
- Substance dependence, drug-related healthcare and social policy diagnosis or label
- Matter, anything that has mass and takes up space
- Substance theory, theory positing that a substance is distinct from its properties
- Substantial (rapper) a US musician
- Substance (Joy Division album), 1988
- Substance (Blank & Jones album), 2002
- Substance 1987, a New Order album
- "Substance", a song by Haste the Day from That They May Know You
- Metal Gear Solid 2: Substance, an update of the video game Metal Gear Solid 2: Sons of Liberty
- Homoousian, a Christian term meaning "same substance"
Famous quotes containing the word substance:
“We are nothing but ceremony; ceremony carries us away, and we leave the substance of things; we hang on to the branches and abandon the trunk and body.”
—Michel de Montaigne (1533–1592)
“What makes literature interesting is that it does not survive its translation. The characters in a novel are made out of the sentences. That’s what their substance is.”
—Jonathan Miller (b. 1936)
“I do not remember anything which Confucius has said directly respecting man’s “origin, purpose, and destiny.” He was more practical than that. He is full of wisdom applied to human relations,—to the private life,—the family,—government, etc. It is remarkable that, according to his own account, the sum and substance of his teaching is, as you know, to do as you would be done by.”
—Henry David Thoreau (1817–1862)