Substance may refer to:
- Chemical substance, a material with a definite chemical composition
- Drug substance
- Substance abuse, drug-related healthcare and social policy diagnosis or label
- Substance dependence, drug-related healthcare and social policy diagnosis or label
- Matter, anything that has mass and takes up space
- Substance theory, theory positing that a substance is distinct from its properties
- Substantial (rapper) a US musician
- Substance (Joy Division album), 1988
- Substance (Blank & Jones album), 2002
- Substance 1987, a New Order album
- "Substance", a song by Haste the Day from That They May Know You
- Metal Gear Solid 2: Substance, an update of the video game Metal Gear Solid 2: Sons of Liberty
- Homoousian, a Christian term meaning "same substance"
Famous quotes containing the word substance:
“Strong be thy wallis that about the standis;
Wise be the people that within the dwellis;
Fresh is thy ryver with his lusty strandis;
Blith be thy chirches, wele sownyng be thy bellis;
Riche be thy merchauntis in substance that excellis
Fair be thy wives, right lovesom, white and small;
Clere be thy virgyns, lusty under kellis:
London, thou art the flour of Cities all.”
—William Dunbar (c. 1465–c. 1530)
“But they that hold God to be [an incorporeal substance] ... do absolutely make God to be nothing at all. But how? Were they atheists? No. For though by ignorance of the consequence they said that which was equivalent to atheism, yet in their hearts they thought God a substance ... So that this atheism by consequence is a very easy thing to be fallen into, even by the most godly men of the church.”
—Thomas Hobbes (1588–1679)