What is herg?

HERG

hERG (the human Ether-à-go-go-Related Gene) is a gene (KCNH2) that codes for a protein known as Kv11.1, the alpha subunit of a potassium ion channel. This ion channel (sometimes simply denoted as 'hERG') is best known for its contribution to the electrical activity of the heart that coordinates the heart's beating (i.e., the hERG channel mediates the repolarizing IKr current in the cardiac action potential). When this channel's ability to conduct electrical current across the cell membrane is inhibited or compromised, either by application of drugs or by rare mutations in some families, it can result in a potentially fatal disorder called long QT syndrome; a number of clinically successful drugs in the market have had the tendency to inhibit hERG, and create a concomitant risk of sudden death, as a side-effect, which has made hERG inhibition an important antitarget that must be avoided during drug development. hERG has also been associated with modulating the functions of some cells of the nervous system and with establishing and maintaining cancer-like features in leukemic cells.

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Some articles on herg:

Studios Hergé - Works of The Studios
... All works realised under the name of Hergé since 1950 can be considered as works of the Studios ... played a major role, either by colouring, drawing of backgrounds, or by completely replacing Hergé ... correctly judge the role of the contributors, as Hergé and, later, his rights-holders minimized their work ...
HERG - Interactions
... HERG has been shown to interact with YWHAE. ...
Studios Hergé - Works of The Studios - Albums - Pages By Bob De Moor Featuring Hergé
... ne reste jamais impuni, 1 page, (À Suivre...), Hors Série Spécial Hergé, April 1983 De la Planche aux planches, 1 page, Tintin magazine n°43, 1986 (Barelli meets Hergé) ...
Studios Hergé - History
... The Studios Hergé were created by Hergé in 1950 to assist him with the creation of The Adventures of Tintin ... handing over some aspects of the creation, particularly the colouring, which Hergé had never really mastered and which was in the 1940s done by Edgar Pierre Jacobs, and the drawing of ... The Studios were created when Hergé worked on Destination Moon, an adventure where technology was omnipresent ...
Totor
... Scout of the Hannetons is the first comic strip series written by Hergé who later wrote The Adventures of Tintin ... firstly it was for a Scouting magazine, and secondly because Hergé had a great love of the movement ... In 1930 Hergé allowed a comics artist whose pseudonym was Evany (Eugène van Nijverseel) to write Totor on his own, as Hergé was now very busy with his work on Tintin ...