Noteworthy Weyburnites
- Derrick Pouliot - Pittsburgh Penguins 2012 NHL Draft Pick
- Dave "Tiger" Williams - former National Hockey League player
- Graham DeLaet - PGA Tour golfer
- W. O. Mitchell - Canadian writer
- Guy Gavriel Kay - Canadian writer
- Mark Steven Morton - Canadian writer
- Tommy Douglas - Canadian politician credited with the establishment of Medicare in Canada, in 2004, was named “The Greatest Canadian”
- British medical researcher Dr Humphry Osmond - former resident of Weyburn
- Pat Binns - birthplace of the former Premier of Prince Edward Island
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