West Virginia Route 480

West Virginia Route 480 (WV 480) is a state highway in the U.S. state of West Virginia. Known for most of its length as Kearneysville Pike, the state highway runs 5.6 miles (9.0 km) from WV 9 in Kearneysville north to the Maryland state line at the Potomac River in Shepherdstown, where the highway continues as Maryland Route 34 (MD 34). WV 480 is one of the main north–south highways of northern Jefferson County and passes through the campus of Shepherd University.