WSGI and Python 3
The separation of binary and text data in Python 3 poses a problem for WSGI, as it specifies that header data should be strings, while it sometimes needs to be binary and sometimes text. This works in Python 2 where text and binary data both are kept in "string" variables, but in Python 3 binary data is kept in "bytes" variables and "string" variables are for unicode text data. An updated version of the WSGI specification that deals with this is PEP 3333.
A reworked WSGI spec Web3 has also been proposed, specified in PEP444. This standard is an incompatible derivative of WSGI designed to work on Python 2.6, 2.7, 3.1+.
Read more about this topic: Web Server Gateway Interface