Idea
Historically, Python web application frameworks have been a problem for new Python users because, generally speaking, the choice of web framework would limit the choice of usable web servers, and vice versa. Python applications were often designed for either CGI, FastCGI, mod_python or even custom API interfaces of specific web-servers.
WSGI was created as a low-level interface between web servers and web applications or frameworks to promote common ground for portable web application development.
Read more about this topic: Web Server Gateway Interface
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—Henry David Thoreau (1817–1862)