VRS may refer to:
- vara: a unit of length formerly used in Spain and Portugal
- Variable Reluctance Sensor
- Verkehrsverbund Rhein-Sieg: a transport association servicing the Cologne metropolitan area in Germany
- Vermont Rail System
- an alternate abbreviation for Versus: (Vrs.)
- Video Relay Service: a telecommunication service that allows deaf, hard of hearing and speech-impaired individuals to communicate over a videophone (or other videotelecommunication systems such as video-enabled mobile phones) with hearing people via a sign language interpreter
- Virtual Reference Station: uses the RTK solutions from the Trimble RTKNet software to provide high-accuracy, real-time kinematic (RTK) GPS positioning for wider areas
- Virtual Rendering System: a C++ library for the construction of interactive 3D applications.
- Voice Recognition Software
- Vojska Republike Srpske: the Army of Republika Srpska
- Voluntary Retirement Scheme: a Golden handshake scheme offered to employees in India in return for their voluntary retirement.
- Vortex Ring State: an undesirable aerodynamic condition
- vRS: a name given to the sporting Škoda Octavia and Fabia