Casting
The role was originated in April 1992 by actress Cari Shayne. Shayne departed from the series in November 1994 along with her co-star, Antonio Sabàto, Jr. The role was recast in 1997 with Jennifer Hammon who would carry the role over to Port Charles starting in June 1997 and appear on a recurring basis on GH. Hammon last appeared in the role on June 24, 1999 due the difficulty of working on both shows. Marie Wilson assumed the role on June 30, 1999, and maintained Karen's recurring role on GH, last appearing as Karen on July 1, 2003.
Read more about this topic: Victor Collins (General Hospital), Karen Wexler
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