Vena may refer to:
- Virtual Enterprise Network Architecture (VENA) Avaya cloud computing architecture
- Vena (Hindu King)
- Vena Records, a now defunct record label located in Madison, Alabama.
- The Russian spelling of Vienna, Austria.
- The nickname of 2S31 self-propelled 120 mm Russian mortar/cannon.
- Diphenhydramine, by the trade name Vena
- Vein, by Latin
People:
- Cornel Vena (born 1932), Romanian modern pentathlete
- Gary Vena, American academic
- Ryan Vena (born 1977), American football player