Usage
- Angiogenesis
- ↑ Migration of endothelial cells
- ↑ mitosis of endothelial cells
- ↑ Matrix metalloproteinase activity
- ↑ αvβ3 activity
- creation of blood vessel lumen
- creates lumen
- creates fenestrations
- Chemotactic for macrophages and granulocytes
- Vasodilation (indirectly by NO release)
Also tumour suppression.
Read more about this topic: Vascular Endothelial Growth Factor A
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