Valle Grande ("Great Valley" in Spanish) or Vallegrande may refer to:
- Valle Grande Department, one of the Departments of Argentina in Jujuy Province
- Valle Grande, Argentina, the capital city of Valle Grande Department
- Valle Grande, Lanzarote, in the Canary Islands
- Valle Grande, New Mexico, largest grass valley (valle) within the Valles Caldera of New Mexico, USA
- Vallegrande Province, Santa Cruz Department, Bolivia the capitol of the .
- Vallegrande, the capital city of Vallegrande Province