Four ships of the United States Navy have borne the name USS Constellation, in honor, according to the US Congress, of the "new constellation of stars" on the flag of the United States.
- The USS Constellation (1797), was a 38 gun frigate and the second ship to be commissioned in the United States Navy. It was the first US Navy vessel to put to sea and the first US Navy vessel to engage, defeat, and capture an enemy vessel.
- The USS Constellation (1854), was a sloop-of-war that served from 1855 to 1933, and is preserved as a National Historic Landmark in Baltimore, Maryland.
- The USS Constellation (CC-2), a battlecruiser, was laid down in 1920 but construction was canceled in 1923.
- The USS Constellation (CV-64), was a Kitty Hawk-class steam turbine propelled aircraft carrier which served from 1961 to 2003.