U.S. Route 278 In Alabama
U.S. Highway 278 (US-278), mostly internally designated by the Alabama Department of Transportation as State Route 74 (SR-74), is a major east–west state highway across the northern part of the U.S. state of Alabama. West of Hamilton, SR-74 continues west to end at US-78 (SR-4), while US-278 turns south along US-43 (SR-17 and SR-171) to Guin, where it turns west along SR-118 to Mississippi.
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