Urea - History

History

Urea was first discovered in urine in 1727 by the Dutch scientist Herman Boerhaave, though this discovery is often attributed to the French chemist Hilaire Rouelle. In 1828, the German chemist Friedrich Wöhler obtained urea by treating silver isocyanate with ammonium chloride.

AgNCO + NH4Cl → (NH2)2CO + AgCl

This was the first time an organic compound was artificially synthesized from inorganic starting materials, without the involvement of living organisms. The results of this experiment implicitly discredited vitalism: the theory that the chemicals of living organisms are fundamentally different from inanimate matter. This insight was important for the development of organic chemistry. His discovery prompted Wöhler to write triumphantly to Berzelius: "I must tell you that I can make urea without the use of kidneys, either man or dog. Ammonium cyanate is urea." For this discovery, Wöhler is considered by many the father of organic chemistry.

Read more about this topic:  Urea

Famous quotes containing the word history:

    America is the only nation in history which, miraculously, has gone directly from barbarism to degeneration without the usual interval of civilization.
    Attributed to Georges Clemenceau (1841–1929)

    Properly speaking, history is nothing but the crimes and misfortunes of the human race.
    Pierre Bayle (1647–1706)

    The thing that struck me forcefully was the feeling of great age about the place. Standing on that old parade ground, which is now a cricket field, I could feel the dead generations crowding me. Here was the oldest settlement of freedmen in the Western world, no doubt. Men who had thrown off the bands of slavery by their own courage and ingenuity. The courage and daring of the Maroons strike like a purple beam across the history of Jamaica.
    Zora Neale Hurston (1891–1960)