Notable Alumni
- Ernesto Guevara, physician, former Cuban Minister of Agriculture, revolutionary leader
- Esther Hermitte, anthropologist
- Juan Cabral, film director
- Alberto Prebisch, architect.
- Raul Prebisch, economist.
- Luis Agote, physician.
- Inés Mónica Weinberg de Roca, lawyer, former Judge at the International Criminal Tribunal for Rwanda
- Juan Rosai, physician, Italian-born American surgical pathologist
- Luis Moreno-Ocampo, lawyer, jurist and Chief Prosecutor of the International Criminal Court.
- Julio Cortázar, writer.
- José Luis Murature, foreign minister of Argentina.
- Richard Tomlinson, former British spy.
- Rafael Viñoly, Uruguayan architect.
- Claudio Vekstein, an architect specialized in public architecture.
- Clorindo Testa, an architect and painter.
- Patricio Pouchulu, architect and educator.
- Alberto Calderón, mathematician.
- Luis Caffarelli, mathematician.
- Juan Martín Maldacena, physicist.
The following former students and professors of the university have received the Nobel Prize:
- Carlos Saavedra Lamas, Peace, 1936.
- Adolfo Pérez Esquivel, Peace, 1980.
- Bernardo Houssay, Physiology, 1947.
- Luis Federico Leloir, Chemistry, 1970.
- César Milstein, Medicine, 1984.
The following Presidents of Argentina have earned their degrees at the university:
- Carlos Pellegrini (1890–1892, National Autonomist Party), lawyer.
- Luis Sáenz Peña (1892–1895, National Autonomist Party), lawyer.
- Manuel Quintana (1904–1906, National Autonomist Party), lawyer.
- Roque Sáenz Peña (1910–1914, National Autonomist Party), lawyer.
- Victorino de la Plaza (1914–1916, National Autonomist Party), lawyer.
- Hipólito Yrigoyen (1916–1922 and 1928–1930, Radical Civic Union), lawyer.
- Marcelo Torcuato de Alvear (1922–1928, Radical Civic Union), lawyer.
- Agustín Pedro Justo (1932–1938, "Concordancia" (UCR and PAN)), engineer.
- Roberto Marcelino Ortiz (1938–1942, "Concordancia" (UCR and PAN)), lawyer.
- Ramón Castillo (1942–1943, "Concordancia" (UCR and PAN)), lawyer.
- Arturo Frondizi (1958–1962, Intransigent Radical Civic Union), lawyer.
- Arturo Umberto Illia (1963–1966, People's Radical Civic Union), medic.
- Raúl Alfonsín (1983–1989, Radical Civic Union), lawyer.
- Adolfo Rodríguez Saá (2001, Justicialist Party), lawyer.
- Eduardo Duhalde (2002–2003, Justicialist Party), lawyer.
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