Ube2e1

UBE2E1

Identifiers Symbols UBE2E1; UBCH6 External IDs OMIM: 602916 MGI: 107411 HomoloGene: 84372 GeneCards: UBE2E1 Gene EC number 6.3.2.19

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • protein binding • ATP binding • ISG15 ligase activity
Cellular component	• ubiquitin ligase complex • nucleus • nucleoplasm • cytosol
Biological process	• cell cycle checkpoint • M phase of mitotic cell cycle • mitotic anaphase • protein polyubiquitination • mitotic cell cycle • ubiquitin-dependent protein catabolic process • mitotic spindle assembly checkpoint • histone monoubiquitination • protein ubiquitination • cytokine-mediated signaling pathway • anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process • ISG15-protein conjugation • histone H2B ubiquitination • negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle • positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle • regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle • protein K48-linked ubiquitination
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7324 22194 Ensembl ENSG00000170142 ENSMUSG00000021774 UniProt P51965 P52482 RefSeq (mRNA) NM_001202476 NM_009455 RefSeq (protein) NP_001189405 NP_033481 Location (UCSC) Chr 3:
23.85 – 23.93 Mb Chr 14:
18.28 – 18.33 Mb PubMed search

Ubiquitin-conjugating enzyme E2 E1 is a protein that in humans is encoded by the UBE2E1 gene.