Type II Topoisomerase
Type II topoisomerases cut both strands of the DNA helix simultaneously in order to manage DNA tangles and supercoils. They use the hydrolysis of ATP, unlike Type I topoisomerase. In this process, these enzymes change the linking number of circular DNA by ±2.
Read more about Type II Topoisomerase: Function, Topology Simplification, Classification, Structure of Type IIA Topoisomerases, Structures of Type IIB Topoisomerases, Strand Passage Mechanism of Type II Topoisomerases, DNA Cleavage Mechanism of Type IIA Topoisomerases, Catenation, Inhibition
Famous quotes containing the word type:
“Are God and Nature then at strife,
That Nature lends such evil dreams?
So careful of the type she seems,
So careless of the single life;”
—Alfred Tennyson (1809–1892)