Entertainment
- Twitch (film), a 2005 short film directed by Leah Meyerhoff
- Twitch, a 2000 short film featuring Paul Tassone
- Twitch (Ministry album), 1986
- Twitch (Aldo Nova album), 1985
- Twitch (EP), by Jebediah
- Twitch Film, a film website
- TwitchTV, a video streaming website
- Twitch gameplay, a computer or video game in which the player must react quickly
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