Tuohy may refer to:
- Dan Tuohy (born 1985), Irish rugby player
- Denis Tuohy (born 1937), television broadcaster, actor, newsreader, and journalist
- Liam Tuohy (footballer) (born 1933), Irish footballer and manager
- Patrick Tuohy (1894-1930), Irish painter
- An American married couple best known as major figures in the 2009 film The Blind Side:
- Sean Tuohy (born c. 1960), former basketball player, current sportscaster and businessman
- Leigh Anne Tuohy (born c. 1960), interior decorator and businesswoman
- Tom Tuohy (1917-2008), noted for putting out a major fire in Britain's worst nuclear accident
- William Tuohy, American Pulitzer Prize-winning journalist and author
- Tuohy needle, a hypodermic needle
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