TRIM32

TRIM32

Identifiers Symbols TRIM32; BBS11; HT2A; LGMD2H; TATIP External IDs OMIM: 602290 MGI: 1917057 HomoloGene: 36327 GeneCards: TRIM32 Gene

Gene Ontology
Molecular function	• transcription coactivator activity • RNA binding • ubiquitin-protein ligase activity • protein binding • zinc ion binding • myosin binding • Tat protein binding • translation initiation factor binding • ubiquitin binding • protein self-association
Cellular component	• nucleus • cytoplasm • striated muscle myosin thick filament
Biological process	• protein polyubiquitination • response to UV • protein ubiquitination • positive regulation of cell growth • positive regulation of cell migration • response to tumor necrosis factor • protein ubiquitination involved in ubiquitin-dependent protein catabolic process • negative regulation of apoptotic process • innate immune response • fat cell differentiation • positive regulation of neuron differentiation • positive regulation of protein catabolic process • positive regulation of cell cycle • positive regulation of proteolysis • negative regulation of fibroblast proliferation • positive regulation of neurogenesis • positive regulation of NF-kappaB transcription factor activity • positive regulation of cell motility
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 22954 69807 Ensembl ENSG00000119401 ENSMUSG00000051675 UniProt Q13049 Q8CH72 RefSeq (mRNA) NM_001099679 NM_001161782 RefSeq (protein) NP_001093149 NP_001155254 Location (UCSC) Chr 9:
119.45 – 119.46 Mb Chr 4:
65.6 – 65.62 Mb PubMed search

Tripartite motif-containing protein 32 is a protein that in humans is encoded by the TRIM32 gene. Since its discovery in 1995, TRIM32 has been shown to be implicated in a number of diverse biological pathways.