Sub-families
They are encoded by at least 33 channel subunit genes divided into seven sub-families:
- TRPC (canonical) - associated with Focal segmental glomerulosclerosis
- TRPV (vanilloid)
- TRPA (ankyrin)
- TRPM (melastatin) -- associated with Hypomagnesemia with secondary hypocalcemia
- TRPP (polycystin) -- associated with Polycystic kidney disease
- TRPML (mucolipin) -- associated with Mucolipidosis type IV
- TRPN (NOMPC) - no mechanoreceptor potential C - not found in mammals
Read more about this topic: Transient Receptor Potential Channel