Physiological Transglutaminases
Eight transglutaminases have been characterised.
Name | Gene | Activity | Chromosome | OMIM |
---|---|---|---|---|
Factor XIII (fibrin-stabilizing factor) | F13A1, F13B | coagulation | 6p25-p24 | 134570 |
Keratinocyte transglutaminase | TGM1 | skin | 14q11.2 | 190195 |
Tissue transglutaminase | TGM2 | ubiquitous | 20q11.2-q12 | 190196 |
Epidermal transglutaminase | TGM3 | skin | 20q12 | 600238 |
Prostate transglutaminase | TGM4 | prostate | 3p22-p21.33 | 600585 |
TGM X | TGM5 | skin | 15q15.2 | 603805 |
TGM Y | TGM6 | unclear | 20q11-15 | not assigned |
TGM Z | TGM7 | testis, lung | 15q15.2 | 606776 |
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