The TRAMP complex (Trf4/Air2/Mtr4p Polyadenylation complex) is a multi-protein complex consisting of the RNA helicase Mtr4, a poly(A) polymerase (PAP) (either Trf4 or Trf5) and a zinc knuckle protein (either Air1 or Air2). The TRAMP complex interacts with the exosome complex in the nucleus of eukaryotic cells and is involved in the 3' end processing of ribosomal RNA and snoRNAs.
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Famous quotes containing the words tramp and/or complex:
“In the middle classes the gifted son of a family is always the poorest—usually a writer or artist with no sense for speculation—and in a family of peasants, where the average comfort is just over penury, the gifted son sinks also, and is soon a tramp on the roadside.”
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“I have met charming people, lots who would be charming if they hadn’t got a complex about the British and everyone has pleasant and cheerful manners and I like most of the American voices. On the other hand I don’t believe they have any God and their hats are frightful. On balance I prefer the Arabs.”
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