Toxic Capacity Among Humans, Children
Generally people with less mass have a lower toxic capacity than people with larger mass. In particular, children (who have lower mass compared to an adult) are more vulnerable to toxic effects of compounds. The compounds do not have to be poisons but could be medications as well, which is why children's dosages are almost always less than those of an adult, and the overdose danger higher for children.
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—Ellen Galinsky (20th century)