Total Synthesis - Formal Synthesis

Formal Synthesis

A formal synthesis describes not the synthesis of the desired end product but the synthesis of a compound that is already known from the literature to be a precursor to that desired end product. If it is known from the literature that B can be converted to C then a novel route from compound A to compound B is a formal proof that A can also give access to C.

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Famous quotes containing the words formal and/or synthesis:

    Then the justice,
    In fair round belly with good capon lined,
    With eyes severe and beard of formal cut,
    Full of wise saws and modern instances;
    And so he plays his part.
    William Shakespeare (1564–1616)

    The invention of photography provided a radically new picture-making process—a process based not on synthesis but on selection. The difference was a basic one. Paintings were made—constructed from a storehouse of traditional schemes and skills and attitudes—but photographs, as the man on the street put, were taken.
    Jean Szarkowski (b. 1925)