Total Synthesis - Formal Synthesis

Formal Synthesis

A formal synthesis describes not the synthesis of the desired end product but the synthesis of a compound that is already known from the literature to be a precursor to that desired end product. If it is known from the literature that B can be converted to C then a novel route from compound A to compound B is a formal proof that A can also give access to C.

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Famous quotes containing the words formal and/or synthesis:

    “Then the justice,
    In fair round belly with good capon lined,
    With eyes severe and beard of formal cut,
    Full of wise saws and modern instances;
    And so he plays his part.”
    —William Shakespeare (1564–1616)

    “In order to begin an analysis, there must already be a synthesis present in the mind.”
    —Johan Huizinga (1872–1945)