Side Effects
- Hypoglycemia
- Weight gain
- Hypersensitivity- Cross-allergicity with sulfonamide
- Drug Interactions (especially first generation drugs): Increased hypoglycemia with cimetidine, insulin, salicylates, sulfonamides
Salicylates displace tolbutamide from its binding site on plasma binding proteins which lead to increase in free tolbutamide concentration and thus hypoglycemic shock.
Read more about this topic: Tolbutamide
Famous quotes containing the words side and/or effects:
“To be able to see every side of every question;
To be on every side, to be everything, to be nothing long;
To pervert truth, to ride it for a purpose,
To use great feelings and passions of the human family
For base designs, for cunning ends;”
—Edgar Lee Masters (1869–1950)
“The best road to correct reasoning is by physical science; the way to trace effects to causes is through physical science; the only corrective, therefore, of superstition is physical science.”
—Frances Wright (1795–1852)