Side Effects
- Hypoglycemia
- Weight gain
- Hypersensitivity- Cross-allergicity with sulfonamide
- Drug Interactions (especially first generation drugs): Increased hypoglycemia with cimetidine, insulin, salicylates, sulfonamides
Salicylates displace tolbutamide from its binding site on plasma binding proteins which lead to increase in free tolbutamide concentration and thus hypoglycemic shock.
Read more about this topic: Tolbutamide
Famous quotes containing the words side and/or effects:
“To be able to see every side of every question;
To be on every side, to be everything, to be nothing long;
To pervert truth, to ride it for a purpose,
To use great feelings and passions of the human family
For base designs, for cunning ends;”
—Edgar Lee Masters (1869–1950)
“Like the effects of industrial pollution ... the AIDS crisis is evidence of a world in which nothing important is regional, local, limited; in which everything that can circulate does, and every problem is, or is destined to become, worldwide.”
—Susan Sontag (b. 1933)