Side Effects
- Hypoglycemia
- Weight gain
- Hypersensitivity- Cross-allergicity with sulfonamide
- Drug Interactions (especially first generation drugs): Increased hypoglycemia with cimetidine, insulin, salicylates, sulfonamides
Salicylates displace tolbutamide from its binding site on plasma binding proteins which lead to increase in free tolbutamide concentration and thus hypoglycemic shock.
Read more about this topic: Tolbutamide
Famous quotes containing the words side and/or effects:
“O, the world hath not a sweeter creature! She might lie by an emperor’s side and command him tasks.”
—William Shakespeare (1564–1616)
“Corporate America will likely be motivated to support child care when it can be shown to have positive effects on that which management is concerned about—recruitment, retention and productivity. Indeed, employers relate to child care as a way to provide growth fostering environments for young managers.”
—Dana E. Friedman (20th century)