Scientific Focus
Tobias Bonhoeffer's scientific research is focused on the cellular foundations of learning and memory, as well as on the early postnatal development of the brain.
Tobias Bonhoeffer's work led to a number of important scientific discoveries. Among these are:
- the optical verification of the existence of "pinwheels" in the mammalian visual system via high-resolution microscopic techniques. (Bonhoeffer & Grinvald, Nature 1991)
- the proof that neurotrophins, and in particular the brain-derived neurotrophic factor (BDNF), play a central role in synaptic plasticity. (Korte et al., PNAS 1995 & 1996)
- the observation that the functional strengthening of synapses goes along with morphological changes of the nerve cell, more specifically with the formation of dendritic spines. (Engert & Bonhoeffer, Nature 1999)
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