Treatment
Tinea cruris is best treated with topical antifungal medications of the allylamine or azole type. These anti-fungal agents stop fungi from producing ergosterol, an essential component of fungal cell membranes. If ergosterol synthesis is completely or partially inhibited, the fungal cell is unable to construct an intact cell membrane, and dies. Allylamines and thiocarbamate antifungals (tolnaftate, Tinactin etc.) are effective against Tinea cruris, but not against Candida albicans, which requires an azole type drug, making azole drugs, effective against both types of infections, the first choice for topical treatment of infections of unknown etiology in intertriginous areas.
If the skin inflammation causes discomfort and itching, glucocorticoid steroids (such as 1% hydrocortisone cream) may be combined with the anti-fungal drug to help prevent further irritation due to the patient scratching the area. Apart from the quicker relief of symptoms, this also helps minimize the risk of secondary bacterial infection caused by the scratching. However, steroids may exacerbate the condition if used alone for fungal infections because they hinder the body's immune system.
Since fungi tend to thrive in warm, dark, damp conditions, minimizing these conditions can help treat and prevent this rash. Some useful measures are: wearing boxer underwear or no underwear, increasing air-flow by sleeping near a fan, wearing loose sleepwear or no sleepwear, exposing the area to wind and sun, and thoroughly cleaning the area with a hand-held showerhead and soap.
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