Health
Unlike most large breeds, its life expectancy is long, some 10–14 years - at least in some lines. Other, more closely inbred lines, produce short-lived, unhealthy dogs. The breed has fewer genetic health problems than many breeds, but cases can be found of hypothyroidism, entropion, ectropion, skin problems including allergies, autoimmune problems including demodex, missing teeth, malocclusion (overbite or underbite), cardiac problems, epilepsy, progressive retinal atrophy (PRA), cataract, and small ear canals with a tendency for infection. As with most large breeds, some will suffer with elbow or hip dysplasia.
Canine inherited demyelinative neuropathy (CIDN), an inherited condition, appeared in one of the prominent lines of Tibetan Mastiffs in the early 1980s. Unfortunately, known carriers were bred extensively and are behind many lines still being actively bred.
Hypothyroidism is fairly common in Tibetan Mastiffs, as it is in many large "northern" breeds. They should be tested periodically throughout their lives using a complete thyroid "panel". (Simple T2/T4 testing is virtually useless.) However, because the standard thyroid levels were established using domestic dog breeds, test results must be considered in the context of what is "normal" for the breed, not what is normal across all breeds. Many dogs of this breed will have "low" thyroid values but no clinical symptoms. Vets and owners differ on the relative merits of medicating dogs which test "low", but are completely asymptomatic. Some researchers think that asymptomatic hypothyroidism may have been adaptive in the regions of origin for many breeds, since less nutrition is required for the dog to stay in good condition. Therefore, attempts to eliminate "low thyroid" dogs from the Tibetan Mastiff gene pool may have unintended consequences for the breed.
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