Stimulation and Inhibition
TPO is stimulated by TSH, which upregulates gene expression.
TPO is inhibited by the thioamide drugs, such as propylthiouracil and methimazole. In laboratory rats with insufficient iodine intake, inhibition of TPO has also been demonstrated for genistein.
Read more about this topic: Thyroid Peroxidase
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—Willard Van Orman Quine (b. 1908)