Thyroid Peroxidase - Catalyzed Reaction

Catalyzed Reaction

2 + 2 Iāˆ’ + H2O2 ⇒ 2 + 2 H2O

Iodide is oxidized to iodine radical which immediately reacts with tyrosine.

2 + 2 Iāˆ’ + H2O2 ⇒ 2 + 2 H2O

The second iodine atom is added in similar manner to the reaction intermediate 3-iodotyrosine.

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