Function
It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of myeloid (CD11c+) dendritic cells. TSLP has also been shown to activate maturation of specific subset of dendritic cells located within the epidermis, Langerhans cell. Within the thymus TSLP activation of both myeloid and plasmacytoid (CD123+) dendritic cells results in the production of regulatory T cells.
Read more about this topic: Thymic Stromal Lymphopoietin
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