Presence in Human and Mouse
The enzyme is synthesized and functional in mice.
Humans also have the remnants of the gene, coding this enzyme (GLY1), however it is damaged by past mutations and inactive. Human gene contains two single nucleotide deletions causing frameshifts and premature stop codons. Also, the encoded protein would not be active anyway due mutations in other highly conserved regions. Human gene is no longer transcribed into RNA.
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Famous quotes containing the words presence, human and/or mouse:
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—Herman Melville (1819–1891)
“Sensuality reconciles us with the human race. The misanthropy of the old is due in large part to the fading of the magic glow of desire.”
—Eric Hoffer (1902–1983)
“It is as when a migrating army of mice girdles a forest of pines. The chopper fells trees from the same motive that the mouse gnaws them,—to get his living. You tell me that he has a more interesting family than the mouse. That is as it happens.”
—Henry David Thoreau (1817–1862)