| EC number | Name | Alternate name | Isozymes | Subcellular distribution |
|---|---|---|---|---|
| EC 2.3.1.9 | Acetyl-CoA C-acetyltransferase | thiolase II; Acetoacetyl-CoA thiolase |
ACAT1 | mitochondrial |
| ACAT2 | cytosolic | |||
| EC 2.3.1.16 | Acetyl-CoA C-acyltransferase | thiolase I; 3-Ketoacyl-CoA thiolase; β-Ketothiolase |
ACAA1 | peroxisomal |
| ACAA2 | mitochondrial | |||
| HADHB | mitochondrial | |||
| EC 2.3.1.154 | Propionyl-CoA C2-trimethyltridecanoyltransferase | 3-Oxopristanoyl-CoA thiolase | ||
| EC 2.3.1.174 | 3-Oxoadipyl-CoA thiolase | β-Ketoadipyl-CoA thiolase | ||
| EC 2.3.1.176 | Propanoyl-CoA C-acyltransferase | Peroxisomal thiolase 2 | SCP2 | peroxisomal/cytosolic |
Mammalian nonspecific lipid-transfer protein (nsL-TP) (also known as sterol carrier protein 2) is a protein which seems to exist in two different forms: a 14 Kd protein (SCP-2) and a larger 58 Kd protein (SCP-x). The former is found in the cytoplasm or the mitochondria and is involved in lipid transport; the latter is found in peroxisomes. The C-terminal part of SCP-x is identical to SCP-2 while the N-terminal portion is evolutionary related to thiolases.
Read more about this topic: Thiolase