Pathway Regulation
The TGF beta signaling pathway is involved in a wide range of cellular process and subsequently is very heavily regulated. There are a variety of mechanisms where the pathway is modulated either positively or negatively: There are agonists for ligands and R-SMADs; there are decoy receptors; and R-SMADs and receptors are ubiquitinated.
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Famous quotes containing the words pathway and/or regulation:
“Many are obstinate with regard to the pathway once they have set upon it, few with regard to the goal.”
—Friedrich Nietzsche (1844–1900)
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—David Hume (1711–1776)