TFRC

TFRC

Identifiers Symbols TFRC; CD71; T9; TFR; TFR1; TR; TRFR; p90 External IDs OMIM: 190010 MGI: 98822 HomoloGene: 2429 GeneCards: TFRC Gene

Gene Ontology
Molecular function transferrin receptor activity
protein binding
peptidase activity
Cellular component extracellular region
endosome
plasma membrane
integral to plasma membrane
coated pit
external side of plasma membrane
membrane
cytoplasmic membrane-bounded vesicle
melanosome
perinuclear region of cytoplasm
extracellular vesicular exosome
Biological process proteolysis
cellular iron ion homeostasis
virus-host interaction
osteoclast differentiation
transferrin transport
positive regulation of bone resorption
transmembrane transport
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7037 22042 Ensembl ENSG00000072274 ENSMUSG00000022797 UniProt P02786 Q62351 RefSeq (mRNA) NM_001128148 NM_011638 RefSeq (protein) NP_001121620 NP_035768 Location (UCSC) Chr 3:
195.75 – 195.81 Mb Chr 16:
32.61 – 32.63 Mb PubMed search

Transferrin receptor protein 1 (TfR1) also known as (Cluster of Differentiation 71) (CD71) is a protein that in humans is encoded by the TFRC gene. TfR1 is required for iron delivery from transferrin to cells.

Read more about TFRC:  Clinical Significance, Interactions, See Also