History of Testicular Immunology
- 460-377 BC Hippocrates described testicular inflammation associated with mumps
- 1785 Hunter and Michaelis performed transplant experiments in domestic chickens
- 1849 Berthold transplanted testes between roosters and showed maintenance of male sex characteristics only in birds with successfully grafted testes
- 1899-1900 Sperm recognized as immunogenic (will cause an autoimmune reaction if transplanted from the testis into a different area of the body) by Lansteiner (1899) and Metchinikoff, (1900)
- 1913-1914 Human testis transplants performed by Lespinasse (1913), and Lydson (1914) who performed a graft on himself!
- 1954 Discovery that sperm autoantibodies contribute to infertility,
- 1977 Billingham recognized that the testis is site of immune privilege
Read more about this topic: Testicular Immunology
Famous quotes containing the words history of, history and/or testicular:
“The history of persecution is a history of endeavors to cheat nature, to make water run up hill, to twist a rope of sand.”
—Ralph Waldo Emerson (1803–1882)
“The history of the Victorian Age will never be written: we know too much about it.”
—Lytton Strachey (1880–1932)
“... the Ovarian Theory of Literature, or, rather, its complement, the Testicular Theory. A recent camp follower ... of this explicit theory is ... Norman Mailer, who has attributed his own gift, and the literary gift in general, solely and directly to the possession of a specific pair of organs. One writes with these organs, Mailer has said ... and I have always wondered with what shade of ink he manages to do it.”
—Cynthia Ozick (b. 1928)