Genetic Defects
Most testicular germ cell tumors have too many chromosomes, and most often they are triploid to tetraploid. An isochromosome 12p (the short arm of chromosome 12 on both sides of the same centromere) is present in about 80% of the testicular cancers, and also the other cancers usually have extra material from this chromosome arm through other mechanisms of genomic amplification.
Read more about this topic: Testicular Cancer
Famous quotes containing the words genetic and/or defects:
“Nature, we are starting to realize, is every bit as important as nurture. Genetic influences, brain chemistry, and neurological development contribute strongly to who we are as children and what we become as adults. For example, tendencies to excessive worrying or timidity, leadership qualities, risk taking, obedience to authority, all appear to have a constitutional aspect.”
—Stanley Turecki (20th century)
“The defects and faults of the mind are like wounds in the body; after all imaginable care has been taken to heal them up, still there will be a scar left behind, and they are in continual danger of breaking the skin and bursting out again.”
—François, Duc De La Rochefoucauld (1613–1680)