Genetic Defects
Most testicular germ cell tumors have too many chromosomes, and most often they are triploid to tetraploid. An isochromosome 12p (the short arm of chromosome 12 on both sides of the same centromere) is present in about 80% of the testicular cancers, and also the other cancers usually have extra material from this chromosome arm through other mechanisms of genomic amplification.
Read more about this topic: Testicular Cancer
Famous quotes containing the words genetic and/or defects:
“Man is not merely the sum of his masks. Behind the shifting face of personality is a hard nugget of self, a genetic gift.... The self is malleable but elastic, snapping back to its original shape like a rubber band. Mental illness is no myth, as some have claimed. It is a disturbance in our sense of possession of a stable inner self that survives its personae.”
—Camille Paglia (b. 1947)
“The defects and faults of the mind are like wounds in the body; after all imaginable care has been taken to heal them up, still there will be a scar left behind, and they are in continual danger of breaking the skin and bursting out again.”
—François, Duc De La Rochefoucauld (1613–1680)