Abuse Potential
From Janssen Pharmaceuticals, Inc: "NUCYNTA® is a mu-opioid agonist and is a Schedule II controlled substance. Such drugs are sought by drug abusers and people with addiction disorders. Diversion of Schedule II products is an act subject to criminal penalty. NUCYNTA® can be abused in a manner similar to other mu-opioid agonists, legal or illicit. This should be considered when prescribing or dispensing NUCYNTA® in situations where the physician or pharmacist is concerned about an increased risk of misuse and abuse. All patients treated with mu-opioid agonists require careful monitoring for signs of abuse and addiction. NUCYNTA® may be abused by crushing, chewing, snorting or injecting the product. These practices pose a significant risk to the abuser that could result in overdose and death." Patients with a history of drug or alcohol abuse are believed to have a higher risk of abusing NUCYNTA®, as with other mu-opioid agonists.
Although early pre-clinical animal trials suggested that NUCYNTA® has a reduced abuse liability compared to other opioid analgesics, it has since been determined to be no less abusable than other pure-form opioid preparations. The US DEA has placed tapentadol into Schedule II, the same category as the most powerful and frequently abused narcotics, such as morphine, oxycodone and fentanyl.
Read more about this topic: Tapentadol
Famous quotes containing the words abuse and/or potential:
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