Tapasin

Tapasin

Identifiers Symbols TAPBP; NGS17; TAPA; TPN; TPSN External IDs OMIM: 601962 MGI: 1201689 HomoloGene: 2401 GeneCards: TAPBP Gene

Gene Ontology
Molecular function	• protein binding • peptide antigen-transporting ATPase activity • MHC class I protein binding • peptide antigen binding • TAP1 binding • TAP2 binding • unfolded protein binding
Cellular component	• Golgi membrane • endoplasmic reticulum • endoplasmic reticulum membrane • integral to membrane • MHC class I peptide loading complex • TAP complex • integral to lumenal side of endoplasmic reticulum membrane
Biological process	• antigen processing and presentation of peptide antigen via MHC class I • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • protein complex assembly • retrograde vesicle-mediated transport, Golgi to ER • defense response • immune response • antigen processing and presentation of endogenous peptide antigen via MHC class I • antigen processing and presentation of exogenous peptide antigen via MHC class I • peptide antigen stabilization
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 6892 21356 Ensembl ENSG00000112493 ENSMUSG00000024308 UniProt O15533 Q9R233 RefSeq (mRNA) NM_003190 NM_001025313 RefSeq (protein) NP_003181 NP_001020484 Location (UCSC) Chr 6:
33.27 – 33.28 Mb Chr 17:
33.92 – 33.93 Mb PubMed search

TAP-associated glycoprotein also known as tapasin or TAPBP is a protein that in humans is encoded by the TAPBP gene.