Takedown or take down may refer to:
- Takedown (book), a book by John Markoff and Tsutomu Shimomura about the capture of Kevin Mitnick
- Track Down, a 2000 film based thereon, known also as Takedown
- The Takedown, a book by Jeffrey Robinson subtitled, "A Suburban Mom, A Coal Miner's Son, and the Unlike Demise of Colombia's Brutal Norte Valle Cartel."
- Take Down (film), a 1979 film about a high school wrestling team
- Takedown (grappling), a martial arts technique
- A colostomy takedown or reversal
- Takedown (Transformers), a fictional character
- Takedown gun, a rifle or shotgun designed for easy dis-assembly
- Bad Boys: Miami Takedown, a 2004 video game based on the film Bad Boys
- Burnout 3: Takedown, a 2004 video and arcade game of the Burnout series
- Notice and take down, for example a sent pursuant to the Online Copyright Infringement Liability Limitation Act, part of the Digital Millennium Copyright Act
- Words taken down, an objection to speech in the United States House of Representatives
- A legal search and seizure or enforced removal of material from a website or other on-line digital service