T7 DNA Helicase - Crystal Structure

Crystal Structure

The crystal structure was solved to 3.0 Å resolution in 2000, as shown in the figure. In (A), notice that the separate subunits appear to be anchored through interactions between an alpha helix and an adjacent subunit. In (B), there are six sets of three loops. The red loop, known as loop II, contains three lysine residues and is thought to be involved in binding the ssDNA that is fed through the center of the enzyme.

Read more about this topic:  T7 DNA Helicase

Famous quotes containing the words crystal and/or structure:

    If Los Angeles has been called “the capital of crackpots” and “the metropolis of isms,” the native Angeleno can not fairly attribute all of the city’s idiosyncrasies to the newcomer—at least not so long as he consults the crystal ball for guidance in his business dealings and his wife goes shopping downtown in beach pajamas.
    —For the State of California, U.S. public relief program (1935-1943)

    A special feature of the structure of our book is the monstrous but perfectly organic part that eavesdropping plays in it.
    Vladimir Nabokov (1899–1977)