Sweetie or Sweety may refer to:
- Sweetie (term of endearment)
- Sweetie, a 1929 college musical film starring Helen Kane, Jack Oakie, and Nancy Carroll
- Sweetie (film), a 1989 Australian film
- Oroblanco or sweetie, a fruit that is a cross between an acidless pummelo and a white grapefruit
- Sweety, a Mandopop band
- "Sweetie", a 2006 Japanese song by Fumiko Orikasa
- Sweetie Irie (born 1971), British reggae singer and DJ born Dean Bent
- Sweety Kapoor, British music promoter
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