Criticism
There have been a number of instances when studies using surrogate markers have been used to show benefit from a particular treatment, but later, a repeat study looking at endpoints has not shown a benefit, or even a harm.
Read more about this topic: Surrogate Endpoint
Famous quotes containing the word criticism:
“Of all the cants which are canted in this canting worldthough the cant of hypocrites may be the worstthe cant of criticism is the most tormenting!”
—Laurence Sterne (17131768)
“Good criticism is very rare and always precious.”
—Ralph Waldo Emerson (18031882)
“A friend of mine spoke of books that are dedicated like this: To my wife, by whose helpful criticism ... and so on. He said the dedication should really read: To my wife. If it had not been for her continual criticism and persistent nagging doubt as to my ability, this book would have appeared in Harpers instead of The Hardware Age.”
—Brenda Ueland (18911985)