Supremium
Supremium is the source of Supreme's power. As a child, Ethan Crane found a meteorite composed of pure Supremium, which turned his hair white and gave him many super-powers, such as flight, invulnerability, super-strength, super-intelligence, super-speed and more.
Supremium is known to come in different colours, each with a different effect; white Supremium is fatal to Supreme, amber Supremium warps time, onyx Supremium erases time, sapphire Supremium affects probabilities, ruby Supremium transmutes matter, and violet Supremium has random effects.
Supremium existed in a complex timeframe; From Supreme's perspective it existed from 1925, when the Supremium meteorite fell to Earth, until some point in the 1950s when the Supremium Man fused with it and disappeared. The second time Supremium existed was when Supreme synthesized it from trace elements in his blood in the 1960s. The synthetic Supremium existed until the 1990s, when Supreme's arch-enemy Darius Dax merged with it and became the Supremium Man.
Supreme realised that the Supremium Man from the 90s had fallen back in time to the 1950s, and then, upon merging with the remaining Supremium, fallen further back in time, becoming the original meteor.
Supremium is an homage to kryptonite.
Read more about this topic: Supreme (comics)