Human
Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. The first is a dimer (consists of two units), whereas the others are tetramers (four subunits). SOD1 and SOD3 contain copper and zinc, whereas SOD2, the mitochondrial enzyme, has manganese in its reactive centre. The genes are located on chromosomes 21, 6, and 4, respectively (21q22.1, 6q25.3 and 4p15.3-p15.1).
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Read more about this topic: Superoxide Dismutase, Types
Famous quotes containing the word human:
“No Ravens wing can stretch the flight so far
As the torn bandrols of Napoleons war.
Choose then your climate, fix your best abode,
Hell make you deserts and hell bring you blood.
How could you fear a dearth? have not mankind,
Tho slain by millions, millions left behind?
Has not conscription still the power to weild
Her annual faulchion oer the human field?
A faithful harvester!”
—Joel Barlow (17541812)
“The universe appears to me like an immense, inexorable torture-garden.... Passions, greed, hatred, and lies; law, social institutions, justice, love, glory, heroism, and religion: these are its monstrous flowers and its hideous instruments of eternal human suffering.”
—Octave Mirbeau (18501917)
“Ideally, advertising aims at the goal of a programmed harmony among all human impulses and aspirations and endeavors. Using handicraft methods, it stretches out toward the ultimate electronic goal of a collective consciousness.”
—Marshall McLuhan (19111980)