Human
Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. The first is a dimer (consists of two units), whereas the others are tetramers (four subunits). SOD1 and SOD3 contain copper and zinc, whereas SOD2, the mitochondrial enzyme, has manganese in its reactive centre. The genes are located on chromosomes 21, 6, and 4, respectively (21q22.1, 6q25.3 and 4p15.3-p15.1).
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Read more about this topic: Superoxide Dismutase, Types
Famous quotes containing the word human:
“All human life is here, but the Holy Ghost seems to be somewhere else.”
—Anthony Burgess (b. 1917)
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“I am really sorry to see my countrymen trouble themselves about politics. If men were wise, the most arbitrary princes could not hurt them. If they are not wise, the freest government is compelled to be a tyranny. Princes appear to me to be fools. Houses of Commons & Houses of Lords appear to me to be fools; they seem to me to be something else besides human life.”
—William Blake (17571827)