Human
Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. The first is a dimer (consists of two units), whereas the others are tetramers (four subunits). SOD1 and SOD3 contain copper and zinc, whereas SOD2, the mitochondrial enzyme, has manganese in its reactive centre. The genes are located on chromosomes 21, 6, and 4, respectively (21q22.1, 6q25.3 and 4p15.3-p15.1).
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Read more about this topic: Superoxide Dismutase, Types
Famous quotes containing the word human:
“All human beings hang by a thread, an abyss may open under their feet at any moment, and yet they have to go and invent all sorts of difficulties for themselves and spoil their lives.”
—Ivan Sergeevich Turgenev (1818–1883)
“No Raven’s wing can stretch the flight so far
As the torn bandrols of Napoleon’s war.
Choose then your climate, fix your best abode,
He’ll make you deserts and he’ll bring you blood.
How could you fear a dearth? have not mankind,
Tho slain by millions, millions left behind?
Has not conscription still the power to weild
Her annual faulchion o’er the human field?
A faithful harvester!”
—Joel Barlow (1754–1812)
“Writing fiction has developed in me an abiding respect for the unknown in a human lifetime and a sense of where to look for the threads, how to follow, how to connect, find in the thick of the tangle what clear line persists. The strands are all there: to the memory nothing is ever really lost.”
—Eudora Welty (b. 1909)