Role in Cancer
The next section gives a detailed description of Sulf1 and Sulf2’s involvement in cancer. Much of what is known about signaling pathways mediated by Sulfs has been determined through investigating extracellular Sulf role and function in cancer. Therefore, they will be described in tandem. Additionally, this emphasizes how small changes in HS sulfation patterns have major impacts in health and disease.
Read more about this topic: SULF1
Famous quotes containing the words role and/or cancer:
“The role of the stepmother is the most difficult of all, because you can’t ever just be. You’re constantly being tested—by the children, the neighbors, your husband, the relatives, old friends who knew the children’s parents in their first marriage, and by yourself.”
—Anonymous Stepparent. Making It as a Stepparent, by Claire Berman, introduction (1980, repr. 1986)
“We “need” cancer because, by the very fact of its incurability, it makes all other diseases, however virulent, not cancer.”
—Gilbert Adair, British author, critic. “Under the Sign of Cancer,” Myths and Memories (1986)