Role in Cancer
The next section gives a detailed description of Sulf1 and Sulf2’s involvement in cancer. Much of what is known about signaling pathways mediated by Sulfs has been determined through investigating extracellular Sulf role and function in cancer. Therefore, they will be described in tandem. Additionally, this emphasizes how small changes in HS sulfation patterns have major impacts in health and disease.
Read more about this topic: SULF1
Famous quotes containing the words role and/or cancer:
“Mental health data from the 1950’s on middle-aged women showed them to be a particularly distressed group, vulnerable to depression and feelings of uselessness. This isn’t surprising. If society tells you that your main role is to be attractive to men and you are getting crow’s feet, and to be a mother to children and yours are leaving home, no wonder you are distressed.”
—Grace Baruch (20th century)
“Madness is locked beneath. It goes into tissues, is swallowed by the cells. The cells go mad. Cancer is their flag. Cancer is the growth of madness denied.”
—Norman Mailer (b. 1923)